He is joined in South Africa by countrymen Alex Hales, Jason Roy and Tom Curran.
Enoch Nkwe had a moderate first-class playing record, scoring three centuries and averaging 28.06 with the bat in 42 matches
The clean-out comes shortly before a tour of India next month during which South Africa will play
South Africa had gambled on putting Bangladesh, four places below them in the ODI rankings
Hosts England made 311 for eight after being sent into bat by Du Plessis
The Proteas possess a good bowling attack - if they can all stay fit - with Dale Steyn, Kagiso Rabada, Lungi Ngidi and Imran Tahir.
Amla scored 92 runs in 8 innings at the CSA T20 Challenge this year, with an average of 11.5 for the tournament
The ICC found Ikope guilty of breaching three counts of the body's Anti-Corruption Code.
He told the country's officials he will call it quits after the tournament in England
South Africa is still undecided on its best 15 players for the World Cup in May